Tyo, Keith: search on Z-Library

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1

Prospects of yeast systems biology for human health: integrating lipid, protein and energy metabolism

Dina Petranovic, Keith Tyo, Goutham N. Vemuri, Jens Nielsen

Journal:

FEMS Yeast Research

Year:

2010

Language:

english

File:

PDF, 651 KB

english, 2010

2

Stabilized gene duplication enables long-term selection-free heterologous pathway expression

Tyo, Keith E J, Ajikumar, Parayil Kumaran, Stephanopoulos, Gregory

Journal:

Nature Biotechnology

Year:

2009

Language:

english

File:

PDF, 473 KB

english, 2009

3

High-resolution mapping of DNA polymerase fidelity using nucleotide imbalances and next-generation sequencing

de Paz, Alexandra M, Cybulski, Thaddeus R, Marblestone, Adam H, Zamft, Bradley M, Church, George M, Boyden, Edward S, Kording, Konrad P, Tyo, Keith E J

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 1008 KB

english, 2018

4

Characterizing and predicting carboxylic acid reductase activity for diversifying bioaldehyde production

Moura, Matthew, Pertusi, Dante, Lenzini, Stephen, Bhan, Namita, Broadbelt, Linda J., Tyo, Keith E.J.

Journal:

Biotechnology and Bioengineering

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

5

Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development

Rodríguez-Limas, William A, Sekar, Karthik, Tyo, Keith EJ

Journal:

Current Opinion in Biotechnology

Year:

2013

Language:

english

File:

PDF, 1.17 MB

english, 2013

6

CellSort: A support vector machine tool for optimizing fluorescence-activated cell sorting and reducing experimental effort

Yu, Jessica S., Pertusi, Dante A., Adeniran, Adebola V., Tyo, Keith E. J.

Journal:

Year:

2016

Language:

english

File:

PDF, 288 KB

english, 2016

7

Meeting report: Gothenburg Life Science Conference XI – Industrial Systems Biology

Keith E.J. Tyo, Verena Siewers

Journal:

Biotechnology Journal

Year:

2011

Language:

english

File:

PDF, 599 KB

english, 2011

8

Generation and Validation of the iKp1289 Metabolic Model for Klebsiella pneumoniae KPPR1

Henry, Christopher S., Rotman, Ella, Lathem, Wyndham W., Tyo, Keith E. J., Hauser, Alan R., Mandel, Mark J.

Journal:

The Journal of Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 918 KB

english, 2017

9

Detection of a peptide biomarker by engineered yeast receptors

Adeniran, Adebola, Stainbrook, Sarah, Bostick, John, Tyo, Keith

Journal:

ACS Synthetic Biology

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

10

Development of novel metabolite-responsive transcription factors via transposon-mediated protein fusion

Younger, Andrew K D, Su, Peter Y, Shepard, Andrea J, Udani, Shreya V, Cybulski, Thaddeus R, Tyo, Keith E J, Leonard, Joshua N

Journal:

Protein Engineering Design and Selection

Year:

2018

Language:

english

File:

PDF, 810 KB

english, 2018

11

Metabolic kinetic modeling provides insight into complex biological questions, but hurdles remain

Strutz, Jonathan, Martin, Jacob, Greene, Jennifer, Broadbelt, Linda, Tyo, Keith

Journal:

Current Opinion in Biotechnology

Year:

2019

Language:

english

File:

PDF, 361 KB

english, 2019

12

Toward design-based engineering of industrial microbes

Keith EJ Tyo, Kanokarn Kocharin, Jens Nielsen

Journal:

Current Opinion in Microbiology

Year:

2010

Language:

english

File:

PDF, 473 KB

english, 2010

13

Engineering of vesicle trafficking improves heterologous protein secretion in Saccharomyces cerevisiae

Jin Hou, Keith Tyo, Zihe Liu, Dina Petranovic, Jens Nielsen

Journal:

Metabolic Engineering

Year:

2012

Language:

english

File:

PDF, 586 KB

english, 2012

14

Regulatory effects on central carbon metabolism from poly-3-hydroxybutryate synthesis

Sekar, Karthik, Tyo, Keith E.J.

Journal:

Metabolic Engineering

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

15

Evaluating Enzymatic Synthesis of Small Molecule Drugs

Moura, Matthew, Finkle, Justin, Stainbrook, Sarah, Greene, Jennifer, Broadbelt, Linda J., Tyo, Keith E.J.

Journal:

Metabolic Engineering

Year:

2015

Language:

english

File:

PDF, 1.34 MB

english, 2015

16

Expanding the metabolic engineering toolbox: more options to engineer cells

Keith E. Tyo, Hal S. Alper, Gregory N. Stephanopoulos

Journal:

Trends in Biotechnology

Year:

2007

Language:

english

File:

PDF, 362 KB

english, 2007

17

Terpenoids: Opportunities for Biosynthesis of Natural Product Drugs Using Engineered Microorganisms

Ajikumar, Parayil Kumaran, Tyo, Keith, Carlsen, Simon, Mucha, Oliver, Phon, Too Heng, Stephanopoulos, Gregory

Journal:

Molecular Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 347 KB

english, 2008

18

Identification of gene disruptions for increased poly-3-hydroxybutyrate accumulation in Synechocystis PCC 6803

Keith E. J. Tyo, Yong-Su Jin, Freddy A. Espinoza, Gregory Stephanopoulos

Journal:

Biotechnology Progress

Year:

2009

Language:

english

File:

PDF, 583 KB

english, 2009

19

Predicting novel substrates for enzymes with minimal experimental effort with active learning

Pertusi, Dante A., Moura, Matthew E., Jeffryes, James G., Prabhu, Siddhant, Walters Biggs, Bradley, Tyo, Keith E.J.

Journal:

Metabolic Engineering

Year:

2017

Language:

english

File:

PDF, 1.42 MB

english, 2017

20

Exploring De Novo metabolic pathways from pyruvate to propionic acid

Stine, Andrew, Zhang, Miaomin, Ro, Soo, Clendennen, Stephanie, Shelton, Michael C., Tyo, Keith E.J., Broadbelt, Linda J.

Journal:

Biotechnology Progress

Year:

2016

Language:

english

File:

PDF, 472 KB

english, 2016

21

Plasmid-based one-pot saturation mutagenesis

Wrenbeck, Emily E, Klesmith, Justin R, Stapleton, James A, Adeniran, Adebola, Tyo, Keith E J, Whitehead, Timothy A

Journal:

Year:

2016

Language:

english

File:

PDF, 360 KB

english, 2016

22

Acceleration Strategies to Enhance Metabolic Ensemble Modeling Performance

Greene, Jennifer L., Wäechter, Andreas, Tyo, Keith E.J., Broadbelt, Linda J.

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 1.80 MB

english, 2017

23

N-Terminal-Based Targeted, Inducible Protein Degradation in Escherichia coli

Sekar, Karthik, Gentile, Andrew M., Bostick, John W., Tyo, Keith E. J., Herman, Christophe

Journal:

Year:

2016

Language:

english

File:

PDF, 1.85 MB

english, 2016

24

Blocking endocytotic mechanisms to improve heterologous protein titers in Saccharomyces cerevisiae

Rodríguez-Limas, William A., Tannenbaum, Victoria, Tyo, Keith E. J.

Journal:

Biotechnology and Bioengineering

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

25

Yeast-based biosensors: design and applications

Adeniran, Adebola, Sherer, Michael, Tyo, Keith E.J.

Journal:

FEMS Yeast Research

Year:

2014

Language:

english

File:

PDF, 624 KB

english, 2014

26

A high-throughput screen for hyaluronic acid accumulation in recombinant Escherichia coli transformed by libraries of engineered sigma factors

Huimin Yu, Keith Tyo, Hal Alper, Daniel Klein-Marcuschamer, Gregory Stephanopoulos

Journal:

Biotechnology and Bioengineering

Year:

2008

Language:

english

File:

PDF, 581 KB

english, 2008

27

Synthetic biology: Emerging methodologies to catalyze the metabolic engineering design cycle

Christina D. Smolke, Keith E.J. Tyo

Journal:

Metabolic Engineering

Year:

2012

Language:

english

File:

PDF, 94 KB

english, 2012

28

Impact of protein uptake and degradation on recombinant protein secretion in yeast

Tyo, Keith E. J., Liu, Zihe, Magnusson, Ylva, Petranovic, Dina, Nielsen, Jens

Journal:

Applied Microbiology and Biotechnology

Year:

2014

Language:

english

File:

PDF, 1.61 MB

english, 2014

29

Editorial overview: Cell and pathway engineering. Moving from possible to profitable: recent innovations in cell and pathway engineering

Lütke-Eversloh, Tina, Tyo, Keith EJ

Journal:

Current Opinion in Biotechnology

Year:

2014

Language:

english

File:

PDF, 241 KB

english, 2014

30

DNA binding strength increases the processivity and activity of a Y-Family DNA polymerase

Wu, Jing, de Paz, Alexandra, Zamft, Bradley M., Marblestone, Adam H., Boyden, Edward S., Kording, Konrad P., Tyo, Keith E. J.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.65 MB

english, 2017

31

Draft Genome Sequence of a Multidrug-Resistant Klebsiella quasipneumoniae subsp. similipneumoniae Isolate from a Clinical Source

Ozer, Egon A., Morris, Andrew R., Krapp, Fiorella, Henry, Christopher S., Tyo, Keith E., Lathem, Wyndham W., Hauser, Alan R.

Journal:

Genome Announcements

Year:

2016

Language:

english

File:

PDF, 171 KB

english, 2016

32

A Glucose-Sensing Toggle Switch for Autonomous, High Productivity Genetic Control

Bothfeld, William, Kapov, Grace, Tyo, Keith E. J.

Journal:

ACS Synthetic Biology

Year:

2017

Language:

english

File:

PDF, 1.37 MB

english, 2017

33

Analysis of polyhydroxybutyrate flux limitations by systematic genetic and metabolic perturbations

Keith E.J. Tyo, Curt R. Fischer, Fritz Simeon, Gregory Stephanopoulos

Journal:

Metabolic Engineering

Year:

2010

Language:

english

File:

PDF, 681 KB

english, 2010

34

Correction to “Detection of a Peptide Biomarker by Engineered Yeast Receptors”

Adeniran, Adebola, Stainbrook, Sarah, Bostick, John W., Tyo, Keith E. J.

Journal:

ACS Synthetic Biology

Year:

2018

Language:

english

File:

PDF, 267 KB

english, 2018

35

Different expression systems for production of recombinant proteins in Saccharomyces cerevisiae

Zihe Liu, Keith E.J. Tyo, José L. Martínez, Dina Petranovic, Jens Nielsen

Journal:

Biotechnology and Bioengineering

Year:

2012

Language:

english

File:

PDF, 848 KB

english, 2012

36

Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress

Keith EJ Tyo, Zihe Liu, Dina Petranovic, Jens Nielsen

Journal:

Year:

2012

Language:

english

File:

PDF, 658 KB

english, 2012

37

Statistical Analysis of Molecular Signal Recording

Glaser, Joshua I., Zamft, Bradley M., Marblestone, Adam H., Moffitt, Jeffrey R., Tyo, Keith, Boyden, Edward S., Church, George, Kording, Konrad P., Markel, Scott

Journal:

PLoS Computational Biology

Year:

2013

Language:

english

File:

PDF, 766 KB

english, 2013

38

[Methods in Enzymology] Synthetic Biology, Part A Volume 497 || Directed Evolution of Promoters and Tandem Gene Arrays for Customizing RNA Synthesis Rates and Regulation

Tyo, Keith E.J.

Year:

2011

Language:

english

File:

PDF, 463 KB

english, 2011

39

Metabolic kinetic modeling provides insight into complex biological questions, but hurdles remain

Strutz, Jonathan, Martin, Jacob, Greene, Jennifer, Broadbelt, Linda, Tyo, Keith

Journal:

Current Opinion in Biotechnology

Year:

2019

File:

PDF, 361 KB

2019

40

Molecular and process design for rotavirus-like particle production inSaccharomyces cerevisiae

William A Rodríguez-Limas, Keith EJ Tyo, Jens Nielsen, Octavio T Ramírez, Laura A Palomares

Journal:

Microbial Cell Factories

Year:

2011

Language:

english

File:

PDF, 2.19 MB

english, 2011

41

Metabolic engineering of recombinant protein secretion by Saccharomyces cerevisiae

Jin Hou, Keith E.J. Tyo, Zihe Liu, Dina Petranovic, Jens Nielsen

Journal:

FEMS Yeast Research

Year:

2012

Language:

english

File:

PDF, 419 KB

english, 2012

42

Modulating and evaluating receptor promiscuity through directed evolution and modeling

Stainbrook, Sarah C., Yu, Jessica S., Reddick, Michael P., Bagheri, Neda, Tyo, Keith E. J.

Journal:

Protein Engineering Design and Selection

Year:

2017

Language:

english

File:

PDF, 1.05 MB

english, 2017

43

Increased processivity, misincorporation, and nucleotide incorporation efficiency in Sulfolobus solfataricus Dpo4 thumb domain mutations

Wang, Li, Liang, Chenchen, Wu, Jing, Liu, Liming, Tyo, Keith E.J.

Journal:

Applied and Environmental Microbiology

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

44

Model-guided mechanism discovery and parameter selection for directed evolution

Stainbrook, Sarah C., Tyo, Keith E. J.

Journal:

Applied Microbiology and Biotechnology

Year:

2019

Language:

english

File:

PDF, 1.35 MB

english, 2019

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